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| 1603 |
| | | The warlord Tokugawa Ieyasu is awarded the title of shogun, beginning nearly three centuries of the Tokugawa shogunate | |
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| 1613 |
| | | The British East India establishes a 'factory' (a secure warehouse for the storing of Indian goods) at Surat, on the west coast | |
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| 1614 |
| | | An edict is passed expelling Jesuit missionaries from Japan, and ordering their converts to revert to Buddhism | |
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| 1619 |
| | | Jan Pieterszoon Coen destroys the town of Jakarta, on the coast of Java, and rebuilds it as a Dutch trading centre under the name Batavia | |
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| 1624 |
| | | The Japanese are forbidden to leave their country, or foreigners to enter, at the start of more than two centuries of almost total isolation | |
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| c. 1625 |
| | | The Dutch gradually exclude the Portuguese from the immensely lucrative trade in cloves from the Spice Islands (or Moluccas) | |
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| 1641 |
| | | The Dutch expel the Portuguese from their trading posts in Malacca | |
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| 1642 |
| | | The Mongols depose the ruling dynasty of Tibet and offer the country to the Dalai Lama, to be ruled by him with Mongol military support | |
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| 1644 |
| | | The British East India Company completes the construction of Fort St George in Madras | |
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| 1644 |
| | | The last Ming emperor hangs himself, and China acquires a new and final dynasty - the Qing | |
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